Parkinson's Therapeutics

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Drug Therapies

Levodopa = L-DOPA = active ingredient of Sinemet, Stalevo, Madopar, etc.

Intro to levodopa
Why must patients take levodopa so frequently?
Does dietary protein reduce levodopa absorption?
Advanced levodopa pharmacokinetics
Levodopa pharmacokinetics calculator: levodopalevel.com
Are there natural sources of levodopa?
What are the major side effects of levodopa?
Fear of levodopa:  Is it toxic?
Fear of levodopa:  Does it lose its effectiveness?

MAO-B inhibitors

Intro to MAO-B inhibitors
Does rasagiline (Azilect) slow disease progression?
How does safinamide (Xadago) differ from other MAO-B inhibitors?

Other drugs

Dopamine agonists
Nuplazid for Parkinson’s psychosis
Droxidopa for orthostatic hypotension
Amantadine for Parkinson’s symptoms and dyskinesias

Looking to the future

Is a cure imminent?
Imagining the cure

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